Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1228595

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimicrobial activity against Mycobacterium tuberculosis H37Rv assessed as inhibition of bacterial growth in iron-deficient medium after 8 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mycobacterium tuberculosis
Confidence 1 — Organism
Curated By Autocuration

Target

Mycobacterium tuberculosis (CHEMBL360)
Type ORGANISM
Organism Mycobacterium tuberculosis

Publication

Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis.
Ferreras JA, Ryu JS, Di Lello F, Tan DS, Quadri LE.
Nat Chem Biol (2005) 1 : 29 -32
PubMed 16407990 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371502 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371502 IC50 = 2200.0 nM 5.66