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Target Snapshot

CHEMBL360 Target Snapshot

Mycobacterium tuberculosis · ORGANISM · Mycobacterium tuberculosis

Back to Search Search this target Browse approvals Evidence Card
105,154Compounds
9,815Assays
21Approved Drugs
3,282.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-12

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-12
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mycobacterium tuberculosis as ChEMBL target CHEMBL360. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mycobacterium tuberculosis
ORGANISM · Mycobacterium tuberculosis
As of 2026-09-12
ChEMBL target ID
CHEMBL360
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-12
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-12
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mycobacterium tuberculosis still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

Open Review-ready Card
Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameMycobacterium tuberculosis
Target TypeORGANISM
OrganismMycobacterium tuberculosis
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMycobacterium tuberculosis
UniProt AccessionN/A

Mycobacterium tuberculosis

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Mycobacterium tuberculosis.

Review nameMycobacterium tuberculosis
OrganismMycobacterium tuberculosis
Clinical Profile

Clinical Phase Distribution

21
Approved
2
Phase II
Assay Mix

Activity Type Distribution

IC503,014.0
EC50268.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL374478 9.14 IC50 0.72 Approved
CHEMBL43612 8.92 IC50 1.2 Preclinical
CHEMBL3612958 8.6 IC50 2.5 Preclinical
CHEMBL3612953 8.6 IC50 2.5 Preclinical
CHEMBL238592 8.6 IC50 2.5 Preclinical
CHEMBL440047 8.51 IC50 3.1 Preclinical
CHEMBL239662 8.51 IC50 3.1 Preclinical
CHEMBL2282516 8.48 IC50 3.3 Preclinical
CHEMBL238593 8.44 IC50 3.6 Preclinical
CHEMBL2282513 8.41 IC50 3.9 Preclinical
Distribution

pChEMBL Value Distribution

308
5.0
222
5.5
128
6.0
94
6.5
85
7.0
23
7.5
57
8.0
8
8.5
2
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

PRETOMANID
CHEMBL227875
Approved 2019
Properties Compare Identifier
BEDAQUILINE
CHEMBL376488
Approved 2012
Properties Compare Identifier
MOXIFLOXACIN
CHEMBL32
Approved 1999
Properties Compare Identifier
LEVOFLOXACIN
CHEMBL5315124
Approved 1996
Properties Compare Identifier
CIPROFLOXACIN
CHEMBL8
Approved 1987
Properties Compare Identifier
AMIKACIN
CHEMBL177
Approved 1981
Properties Compare Identifier
RIFAMPIN
CHEMBL374478
Approved 1971
Properties Compare Identifier
ISONIAZID
CHEMBL64
Approved 1952
Properties Compare Identifier
Assay Landscape

Assay Landscape

9,826
Total Assays
1,234
Tested Compounds
3
Assay Types
Functional — 9,688 assays, 1,234 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 9,187 1,186 5.3
assay format 492 48 5.9
cell-based format 9 0 —
Binding — 112 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 111 0 —
assay format 1 0 —
ADME — 26 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 20 0 —
organism-based format 6 1 5.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine