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Compound Detail

CHEMBL440047

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Cc1cc(O)c2c(c1)C(=O)C(O)=CC2=O

Basic Information

ChEMBL ID CHEMBL440047
Phase Preclinical
Structure Type MOL
InChI Key KVXSFHXUTPSVOY-UHFFFAOYSA-N
6
Targets
7
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

204.2
MW (Da)
1.52
ALogP
4
HBA
2
HBD
74.6
PSA (Ų)
0.67
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C11H8O4
MW 204.18
Aromatic Rings 1
Heavy Atoms 15
NP-Likeness 1.71

Activity Summary

IC50 7 meas. best 8.51

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Mycobacterium tuberculosis
CHEMBL360
IC50 8.51 8.51 3.1 1
HeLa
CHEMBL399
IC50 5.28 5.28 5300.0 1
DU-145
CHEMBL613508
IC50 5.17 5.17 6800.0 1
MCF7
CHEMBL387
IC50 4.84 4.84 14600.0 1
NON-PROTEIN TARGET
CHEMBL3879801
IC50 4.63 4.63 23200.0 1
PBMC
CHEMBL613107
IC50 4.27 4.27 54000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine