DU-145 · CELL-LINE · Homo sapiens
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DU-145
Review this target as DU-145.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DU-145 as ChEMBL target CHEMBL613508. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | DU-145 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as DU-145.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1808826 | 10.37 | IC50 | 0.043 | Preclinical |
| CHEMBL159 | 10.2 | IC50 | 0.063 | Approved |
| CHEMBL92 | 10.0 | IC50 | 0.1 | Approved |
| CHEMBL269081 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL1808824 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL1808829 | 9.62 | IC50 | 0.24 | Preclinical |
| CHEMBL1288638 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL1808822 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL554604 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL5206589 | 9.48 | IC50 | 0.33 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3,868 | 6,247 | 5.4 |
| organism-based format | 116 | 2 | 6.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 109 | 22 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |