Assay Detail
ADMET
CHEMBL3368694
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Cytotoxicity against human PBMC assessed as cell survival after 24 hrs by XTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxicity of synthesized 1,4-naphthoquinone analogues on selected human cancer cell lines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.51 | 4.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL430853 | RAMENTACEONE | — | 1 | 4.74 |
| CHEMBL440047 | — | — | 1 | 4.27 |
| CHEMBL241784 | 5-FLUORO-8-HYDROXY-6-METHYLNAPHTHALENE-1,4-DIONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL430853 | RAMENTACEONE | IC50 | = | 18400.0 | nM | 4.74 |
| CHEMBL440047 | — | IC50 | = | 54000.0 | nM | 4.27 |
| CHEMBL241784 | 5-FLUORO-8-HYDROXY-6-METHYLNAPHTHALENE-1,4-DIONE | IC50 | = | 188700.0 | nM | - |