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Assay Detail

CHEMBL1228735

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Functional
Antioxidant activity assessed as hydroxyl radical scavenging activity by chemiluminescence analysis
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Antioxidant and anti-inflammatory phenylpropanoid derivatives from Calamus quiquesetinervius.
Chang CL, Zhang LJ, Chen RY, Kuo LM, Huang JP, Huang HC, Lee KH, Wu YC, Kuo YH.
J Nat Prod (2010) 73 : 1482 -1488
PubMed 20825224 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 11 5.00 5.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1224879 QUIQUESETINERVIUSIDE C 1 5.44
CHEMBL153 TROLOX 1 5.37
CHEMBL1224881 1 5.26
CHEMBL1224877 QUIQUESETINERVIUSIDE A 1 5.17
CHEMBL1224878 QUIQUESETINERVIUSIDE B 1 5.13
CHEMBL1224880 QUIQUESETINERVIUSIDE D 1 5.08
CHEMBL1224894 SALCOLIN B 1 4.88
CHEMBL1224884 QUIQUESETINERVIUSIN C 1 4.78
CHEMBL1224885 1 4.72
CHEMBL1224882 QUIQUESETINERVIUSIN A 1 4.62
CHEMBL1224883 QUIQUESETINERVIUSIN B 1 4.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1224879 QUIQUESETINERVIUSIDE C IC50 = 3600.0 nM 5.44
CHEMBL153 TROLOX IC50 = 4310.0 nM 5.37
CHEMBL1224881 IC50 = 5500.0 nM 5.26
CHEMBL1224877 QUIQUESETINERVIUSIDE A IC50 = 6800.0 nM 5.17
CHEMBL1224878 QUIQUESETINERVIUSIDE B IC50 = 7400.0 nM 5.13
CHEMBL1224880 QUIQUESETINERVIUSIDE D IC50 = 8400.0 nM 5.08
CHEMBL1224894 SALCOLIN B IC50 = 13300.0 nM 4.88
CHEMBL1224884 QUIQUESETINERVIUSIN C IC50 = 16600.0 nM 4.78
CHEMBL1224885 IC50 = 19100.0 nM 4.72
CHEMBL1224882 QUIQUESETINERVIUSIN A IC50 = 23700.0 nM 4.62
CHEMBL1224883 QUIQUESETINERVIUSIN B IC50 = 25700.0 nM 4.59