Assay Detail
Functional
CHEMBL1246436
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Cytotoxicity against human H441 cells after 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H441 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and bioactivity of sphingosine kinase inhibitors and their novel aspirinyl conjugated analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.57 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1241156 | — | — | 1 | 6.22 |
| CHEMBL1241832 | — | — | 1 | 5.70 |
| CHEMBL1241831 | — | — | 1 | 5.24 |
| CHEMBL1076555 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1241156 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL1241832 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL1241831 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL1076555 | — | IC50 | = | 8000.0 | nM | 5.10 |