Assay Detail
ADMET
CHEMBL1246440
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MCF10A cells after 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MCF-10A |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and bioactivity of sphingosine kinase inhibitors and their novel aspirinyl conjugated analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.19 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1241156 | — | — | 1 | 5.58 |
| CHEMBL1241832 | — | — | 1 | 5.39 |
| CHEMBL1241831 | — | — | 1 | 4.95 |
| CHEMBL1076555 | — | — | 1 | 4.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1241156 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL1241832 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL1241831 | — | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL1076555 | — | IC50 | = | 14500.0 | nM | 4.84 |