Assay Detail
Functional
CHEMBL1247487
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Cytotoxicity against human HL60 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-cancer activities of diospyrin, its derivatives and analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.33 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243205 | — | — | 1 | 4.52 |
| CHEMBL1242913 | — | — | 1 | 4.27 |
| CHEMBL242992 | — | — | 1 | 4.19 |
| CHEMBL242550 | DIOSPYRIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243205 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL1242913 | — | IC50 | = | 54000.0 | nM | 4.27 |
| CHEMBL242992 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL242550 | DIOSPYRIN | IC50 | > | 100000.0 | nM | - |