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Assay Detail

CHEMBL1249357

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ADMET
Cytotoxicity against activated human CD4+ T cells assessed as cell viability after 5 days by fluorescence detection method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type T-cell
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

A functional genomics approach to the mode of action of apratoxin A.
Luesch H, Chanda SK, Raya RM, DeJesus PD, Orth AP, Walker JR, Izpisúa Belmonte JC, Schultz PG.
Nat Chem Biol (2006) 2 : 158 -167
PubMed 16474387 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.22 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL501696 APRATOXIN A 1 7.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL501696 APRATOXIN A IC50 = 60.0 nM 7.22