Assay Detail
Binding
CHEMBL1250282
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Binding affinity to Cyclin A by competitive binding assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Selectivity and potency of cyclin-dependent kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.83 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217362 | — | — | 1 | 7.30 |
| CHEMBL1241134 | — | — | 1 | 6.28 |
| CHEMBL1241136 | — | — | 1 | 6.23 |
| CHEMBL1241137 | — | — | 1 | 6.17 |
| CHEMBL1241139 | — | — | 1 | 5.25 |
| CHEMBL1241138 | — | — | 1 | 4.92 |
| CHEMBL1241135 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217362 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL1241134 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL1241136 | — | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL1241137 | — | IC50 | = | 680.0 | nM | 6.17 |
| CHEMBL1241139 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL1241138 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL1241135 | — | IC50 | = | 21000.0 | nM | 4.68 |