Assay Detail
Binding
CHEMBL1253103
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]vasopressin from vasopressin V1a receptor in rat liver tissue
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Oral oxytocin antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.93 | 9.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL306645 | — | — | 1 | 9.12 |
| CHEMBL24781 | — | — | 1 | 8.43 |
| CHEMBL296908 | — | — | 1 | 7.50 |
| CHEMBL1253853 | — | — | 1 | 6.96 |
| CHEMBL341490 | — | — | 1 | 5.01 |
| CHEMBL341339 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL306645 | — | Ki | = | 0.76 | nM | 9.12 |
| CHEMBL24781 | — | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL296908 | — | Ki | = | 32.0 | nM | 7.50 |
| CHEMBL1253853 | — | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL341490 | — | Ki | = | 9800.0 | nM | 5.01 |
| CHEMBL341339 | — | Ki | = | 26000.0 | nM | 4.58 |