Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1253142

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]-oxytocin from rat oxytocin receptor expressed in HEK293-EBNA cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Cell Type HEK293-EBNA
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Oxytocin receptor (CHEMBL3996)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Oral oxytocin antagonists.
Borthwick AD.
J Med Chem (2010) 53 : 6525 -6538
PubMed 20550119 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.17 9.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1254117 1 9.17
CHEMBL445816 1 9.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1254117 Ki = 0.67 nM 9.17
CHEMBL445816 Ki = 0.67 nM 9.17