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Assay Detail

CHEMBL1259673

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity against superoxide dismutase like activity after 15 mins by NBT spectrometric assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Fluorinated 2'-hydroxychalcones as garcinol analogs with enhanced antioxidant and anticancer activities.
Padhye S, Ahmad A, Oswal N, Dandawate P, Rub RA, Deshpande J, Swamy KV, Sarkar FH.
Bioorg Med Chem Lett (2010) 20 : 5818 -5821
PubMed 20729081 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.15 5.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1256532 1 5.28
CHEMBL196 ASCORBIC ACID 4.0 1 5.26
CHEMBL1256496 1 5.25
CHEMBL1256531 1 5.22
CHEMBL1256585 1 5.14
CHEMBL339587 1 5.04
CHEMBL1256533 1 4.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1256532 IC50 = 5270.0 nM 5.28
CHEMBL196 ASCORBIC ACID IC50 = 5430.0 nM 5.26
CHEMBL1256496 IC50 = 5680.0 nM 5.25
CHEMBL1256531 IC50 = 6070.0 nM 5.22
CHEMBL1256585 IC50 = 7310.0 nM 5.14
CHEMBL339587 IC50 = 9230.0 nM 5.04
CHEMBL1256533 IC50 = 13680.0 nM 4.86