Assay Detail

CHEMBL1260864

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ADMET

Cytotoxicity against rat L6 cells

ChEMBL ↗

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Target

L6 (CHEMBL614793) ↗

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Primary target L6

CHEMBL614793

Anchored from Assay target.

Protein identity L6

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	ADMET
Organism	Rattus norvegicus
Cell Type	L6
Confidence	1 — Organism
Curated By	Autocuration

Target

L6 (CHEMBL614793) ↗

Type	CELL-LINE
Organism	Rattus norvegicus

Publication

3-alkylthio-1,2,4-triazine dimers with potent antimalarial activity.

Ban K, Duffy S, Khakham Y, Avery VM, Hughes A, Montagnat O, Katneni K, Ryan E, Baell JB.
Bioorg Med Chem Lett (2010) 20 : 6024 -6029
PubMed 20822904 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	4.48	4.48

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL599883	—	—	1	4.48

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL599883	—	EC50	=	33000.0	nM	4.48