Assay Detail
Functional
CHEMBL1272790
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Antioxidant activity of the compound assessed as DPPH radical scavenging activity after 30 mins
17
Total Activities
17
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 17 | 4.52 | 5.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL233929 | GALUTEOLIN | — | 1 | 5.41 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 5.21 |
| CHEMBL1272141 | — | — | 1 | 4.88 |
| CHEMBL509624 | — | — | 1 | 4.81 |
| CHEMBL55415 | SCUTELLAREIN | — | 1 | 4.70 |
| CHEMBL487017 | APIGETRIN | — | 1 | 4.69 |
| CHEMBL1271926 | — | — | 1 | 4.51 |
| CHEMBL1271981 | — | — | 1 | 4.50 |
| CHEMBL1272251 | — | — | 1 | 4.49 |
| CHEMBL469654 | PRUNIN | — | 1 | 4.39 |
| CHEMBL9352 | NARINGENIN | — | 1 | 4.14 |
| CHEMBL1272196 | — | — | 1 | 4.09 |
| CHEMBL487018 | TILIANINE | — | 1 | 4.02 |
| CHEMBL1272142 | — | — | 1 | 4.02 |
| CHEMBL8996 | ERIODICTYOL | — | 1 | 4.00 |
| CHEMBL1272197 | — | — | 1 | - |
| CHEMBL1271925 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL233929 | GALUTEOLIN | EC50 | = | 3940.0 | nM | 5.41 |
| CHEMBL151 | LUTEOLIN | EC50 | = | 6120.0 | nM | 5.21 |
| CHEMBL1272141 | — | EC50 | = | 13150.0 | nM | 4.88 |
| CHEMBL509624 | — | EC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL55415 | SCUTELLAREIN | EC50 | = | 20020.0 | nM | 4.70 |
| CHEMBL487017 | APIGETRIN | EC50 | = | 20370.0 | nM | 4.69 |
| CHEMBL1271926 | — | EC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL1271981 | — | EC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL1272251 | — | EC50 | = | 32150.0 | nM | 4.49 |
| CHEMBL469654 | PRUNIN | EC50 | = | 40600.0 | nM | 4.39 |
| CHEMBL9352 | NARINGENIN | EC50 | = | 72330.0 | nM | 4.14 |
| CHEMBL1272196 | — | EC50 | = | 81170.0 | nM | 4.09 |
| CHEMBL487018 | TILIANINE | EC50 | = | 95000.0 | nM | 4.02 |
| CHEMBL1272142 | — | EC50 | = | 95240.0 | nM | 4.02 |
| CHEMBL8996 | ERIODICTYOL | EC50 | = | 98770.0 | nM | 4.00 |
| CHEMBL1272197 | — | EC50 | = | 159100.0 | nM | - |
| CHEMBL1271925 | — | EC50 | = | 113000.0 | nM | - |