Assay Detail
Binding
CHEMBL1273259
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Inhibition of thrombin
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Factor Xa inhibitors: next-generation antithrombotic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.41 | 8.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1270156 | TANOGITRAN | 2.0 | 1 | 8.57 |
| CHEMBL151939 | — | — | 1 | 5.44 |
| CHEMBL176140 | — | — | 1 | 5.22 |
| CHEMBL351298 | — | — | 1 | - |
| CHEMBL19902 | DX-9065A | — | 1 | - |
| CHEMBL20240 | YM-60828 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1270156 | TANOGITRAN | Ki | = | 2.7 | nM | 8.57 |
| CHEMBL151939 | — | Ki | = | 3600.0 | nM | 5.44 |
| CHEMBL176140 | — | Ki | = | 6000.0 | nM | 5.22 |
| CHEMBL351298 | — | Ki | > | 4000.0 | nM | - |
| CHEMBL19902 | DX-9065A | Ki | > | 2000000.0 | nM | - |
| CHEMBL20240 | YM-60828 | Ki | > | 10000.0 | nM | - |