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Assay Detail

CHEMBL1273311

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to RAP1A in human RBC membrane by Western blot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Ras-related protein Rap-1A (CHEMBL1255139)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Detection of Rap1A as a yessotoxin binding protein from blood cell membranes.
Ujihara S, Oishi T, Mouri R, Tamate R, Konoki K, Matsumori N, Murata M, Oshima Y, Sugiyama N, Tomita M, Ishihama Y.
Bioorg Med Chem Lett (2010) 20 : 6443 -6446
PubMed 20943388 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1077126 YESSOTOXIN 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1077126 YESSOTOXIN Kd = 4000.0 nM 5.40