Assay Detail
ADMET
CHEMBL1273407
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Cytotoxicity against human HeLaS3 cells after 48 hrs by celltiter-glo assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HeLa S3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.24 | 6.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1269812 | — | — | 1 | 6.65 |
| CHEMBL267099 | TUBERCIDIN | — | 1 | 6.40 |
| CHEMBL1269736 | — | — | 1 | 5.66 |
| CHEMBL1269813 | — | — | 1 | - |
| CHEMBL1269814 | — | — | 1 | - |
| CHEMBL1269067 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1269812 | — | IC50 | = | 224.0 | nM | 6.65 |
| CHEMBL267099 | TUBERCIDIN | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL1269736 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL1269813 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1269814 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1269067 | — | IC50 | > | 100000.0 | nM | - |