Assay Detail
Binding
CHEMBL1273734
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Binding affinity to VDR receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel selective anti-androgens with a diphenylpentane skeleton.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.13 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL403885 | — | — | 1 | 7.96 |
| CHEMBL272304 | — | — | 1 | 7.92 |
| CHEMBL403670 | — | — | 1 | 6.50 |
| CHEMBL272502 | — | — | 1 | 6.13 |
| CHEMBL1270149 | — | — | 1 | - |
| CHEMBL1270253 | — | — | 1 | - |
| CHEMBL1270254 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL403885 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL272304 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL403670 | — | Ki | = | 320.0 | nM | 6.50 |
| CHEMBL272502 | — | Ki | = | 740.0 | nM | 6.13 |
| CHEMBL1270149 | — | Ki | - | — | - | |
| CHEMBL1270253 | — | Ki | - | — | - | |
| CHEMBL1270254 | — | Ki | - | — | - |