Assay Detail
Binding
CHEMBL1290881
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Cat K expressed in Ramos cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Ramos |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.76 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1288530 | — | — | 1 | 9.05 |
| CHEMBL1288532 | — | — | 1 | 8.70 |
| CHEMBL1288531 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1288530 | — | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL1288532 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL1288531 | — | IC50 | = | 3.0 | nM | 8.52 |