Assay Detail
ADMET
CHEMBL1291802
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Cytotoxicity against CHO cells by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Artemisinin-quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.46 | 9.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50588 | EMETINE | 4.0 | 1 | 9.72 |
| CHEMBL1288390 | — | — | 1 | 9.17 |
| CHEMBL1288391 | — | — | 1 | 8.27 |
| CHEMBL1288389 | — | — | 1 | 8.00 |
| CHEMBL1288392 | — | — | 1 | 7.13 |
| CHEMBL307261 | ARTENIMOL | 3.0 | 1 | - |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50588 | EMETINE | IC50 | = | 0.19 | nM | 9.72 |
| CHEMBL1288390 | — | IC50 | = | 0.68 | nM | 9.17 |
| CHEMBL1288391 | — | IC50 | = | 5.43 | nM | 8.27 |
| CHEMBL1288389 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL1288392 | — | IC50 | = | 74.82 | nM | 7.13 |
| CHEMBL307261 | ARTENIMOL | IC50 | - | — | - | |
| CHEMBL76 | CHLOROQUINE | IC50 | - | — | - |