Assay Detail
ADMET
CHEMBL1293136
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Cytotoxicity against human NFF after 96 hrs by sulforhodamine B assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | NFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.53 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1289720 | — | — | 1 | 6.77 |
| CHEMBL1289943 | — | — | 1 | 6.58 |
| CHEMBL221654 | — | — | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1289720 | — | IC50 | = | 169.0 | nM | 6.77 |
| CHEMBL1289943 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL221654 | — | IC50 | = | 570.0 | nM | 6.24 |