Assay Detail
Binding
CHEMBL1614222
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: SAR Fluorescence HePTP Assay for Selectivity Study of VHR1 Inhibitors using DiFMUP. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1661, AID1992, AID2004]
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 7 (CHEMBL2219) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.93 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL565795 | — | — | 1 | 6.21 |
| CHEMBL584481 | — | — | 1 | 6.06 |
| CHEMBL567069 | — | — | 1 | 5.92 |
| CHEMBL565810 | — | — | 1 | 5.82 |
| CHEMBL565371 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL565795 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL584481 | — | IC50 | = | 870.0 | nM | 6.06 |
| CHEMBL567069 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL565810 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL565371 | — | IC50 | = | 2400.0 | nM | 5.62 |