Tyrosine-protein phosphatase non-receptor type 7 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P35236. Use UniProt P35236 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P35236 as the stable identity anchor, then attach disease evidence before program review.
Tyrosine-protein phosphatase non-receptor type 7
Review this target as Tyrosine-protein phosphatase non-receptor type 7, mapped to UniProt P35236. Sequence length is 360 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tyrosine-protein phosphatase non-receptor type 7 as ChEMBL target CHEMBL2219, mapped to UniProt P35236. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Tyrosine-protein phosphatase non-receptor type 7 is the right protein anchor across sources, using UniProt P35236 as the stable mapping.
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| Preferred Name | Tyrosine-protein phosphatase non-receptor type 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P35236 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tyrosine-protein phosphatase non-receptor type 7 |
| UniProt Accession | P35236 |
| Component Type | Protein |
| Sequence Length | 360 aa |
Tyrosine-protein phosphatase non-receptor type 7
Review this target as Tyrosine-protein phosphatase non-receptor type 7, mapped to UniProt P35236. Sequence length is 360 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1605172 | 7.84 | IC50 | 14.4 | Preclinical |
| CHEMBL1322542 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL1408579 | 7.46 | IC50 | 34.5 | Preclinical |
| CHEMBL1304193 | 7.23 | IC50 | 58.6 | Preclinical |
| CHEMBL1460470 | 7.18 | IC50 | 66.0 | Preclinical |
| CHEMBL1608642 | 7.07 | IC50 | 84.6 | Preclinical |
| CHEMBL1360024 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL1445488 | 6.98 | IC50 | 105.0 | Preclinical |
| CHEMBL1505246 | 6.97 | IC50 | 108.0 | Preclinical |
| CHEMBL454668 | 6.9 | IC50 | 125.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 34 | 37 | 5.2 |
| cell-based format | 15 | 2 | 4.2 |
| assay format | 13 | 21 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 302 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |