Assay Detail
Functional
CHEMBL1614305
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PUBCHEM_BIOASSAY: Counterscreen for vasopressin 1 receptor (V1R) agonists: Fluorescence-based cell-based high throughput dose response assay for agonists of the Oxytocin Receptor (OXTR). (Class of assay: confirmatory) [Related pubchem assays: 2435 (Primary screen (OXTR agonists in singlicate)), 434964 (Confirmation screen (V1R agonists in triplicate)), 434969 (Counterscreen (OXTR agonists in triplicate)), 2797 (Counterscreen (V1R agonists in singlicate))]
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Category | confirmatory |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 12 | 4.79 | 4.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276711 | SEMAXANIB | 3.0 | 1 | 4.94 |
| CHEMBL473106 | — | — | 1 | 4.78 |
| CHEMBL3189462 | — | — | 1 | 4.66 |
| CHEMBL1420311 | — | — | 1 | - |
| CHEMBL1341433 | — | — | 1 | - |
| CHEMBL1557186 | — | — | 1 | - |
| CHEMBL1479813 | — | — | 1 | - |
| CHEMBL1492232 | — | — | 1 | - |
| CHEMBL1996343 | — | — | 1 | - |
| CHEMBL1580769 | — | — | 1 | - |
| CHEMBL1584768 | — | — | 1 | - |
| CHEMBL2004487 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276711 | SEMAXANIB | EC50 | = | 11468.0 | nM | 4.94 |
| CHEMBL473106 | — | EC50 | = | 16681.0 | nM | 4.78 |
| CHEMBL3189462 | — | EC50 | = | 21762.0 | nM | 4.66 |
| CHEMBL1420311 | — | EC50 | > | 9969.0 | nM | - |
| CHEMBL1341433 | — | EC50 | > | 9971.0 | nM | - |
| CHEMBL1557186 | — | EC50 | > | 29931.0 | nM | - |
| CHEMBL1479813 | — | EC50 | > | 29904.0 | nM | - |
| CHEMBL1492232 | — | EC50 | > | 3323.0 | nM | - |
| CHEMBL1996343 | — | EC50 | > | 29909.0 | nM | - |
| CHEMBL1580769 | — | EC50 | > | 29906.0 | nM | - |
| CHEMBL1584768 | — | EC50 | > | 29908.0 | nM | - |
| CHEMBL2004487 | — | EC50 | > | 29916.0 | nM | - |