Assay Detail
Functional
CHEMBL1614453
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Response HTS Screen to Identify Cytotoxic Compounds of NIH3T3 cells. (Class of assay: confirmatory) [Related pubchem assays: 1885, 1968 ]
4026
Total Activities
4024
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | NIH3T3 |
| Category | confirmatory |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4026 | 5.11 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1467533 | — | — | 1 | 6.92 |
| CHEMBL1473676 | — | — | 1 | 6.77 |
| CHEMBL3191989 | — | — | 1 | 6.72 |
| CHEMBL600778 | — | — | 1 | 6.72 |
| CHEMBL1498488 | — | — | 1 | 6.60 |
| CHEMBL592600 | — | — | 1 | 6.37 |
| CHEMBL1990071 | — | — | 1 | 6.37 |
| CHEMBL1476215 | — | — | 1 | 6.37 |
| CHEMBL601768 | — | — | 1 | 6.37 |
| CHEMBL1532068 | — | — | 1 | 6.36 |
| CHEMBL2000517 | — | — | 1 | 6.31 |
| CHEMBL1328792 | — | — | 1 | 6.31 |
| CHEMBL1304363 | — | — | 1 | 6.30 |
| CHEMBL586135 | — | — | 1 | 6.30 |
| CHEMBL22062 | — | — | 1 | 6.27 |
| CHEMBL3197177 | — | — | 1 | 6.27 |
| CHEMBL607140 | — | — | 1 | 6.26 |
| CHEMBL590665 | — | — | 1 | 6.24 |
| CHEMBL1544633 | — | — | 1 | 6.24 |
| CHEMBL1373096 | — | — | 1 | 6.23 |
| CHEMBL547285 | — | — | 1 | 6.23 |
| CHEMBL1514530 | — | — | 1 | 6.21 |
| CHEMBL2094567 | — | — | 1 | 6.18 |
| CHEMBL1570765 | — | — | 1 | 6.17 |
| CHEMBL1448282 | — | — | 1 | 6.16 |
| CHEMBL1548492 | — | — | 1 | 6.14 |
| CHEMBL1983418 | — | — | 1 | 6.12 |
| CHEMBL1490222 | — | — | 1 | 6.12 |
| CHEMBL1541973 | — | — | 1 | 6.10 |
| CHEMBL1424665 | — | — | 1 | 6.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1467533 | — | EC50 | = | 121.0 | nM | 6.92 |
| CHEMBL1473676 | — | EC50 | = | 171.0 | nM | 6.77 |
| CHEMBL600778 | — | EC50 | = | 192.0 | nM | 6.72 |
| CHEMBL3191989 | — | EC50 | = | 192.0 | nM | 6.72 |
| CHEMBL1498488 | — | EC50 | = | 253.0 | nM | 6.60 |
| CHEMBL592600 | — | EC50 | = | 424.0 | nM | 6.37 |
| CHEMBL601768 | — | EC50 | = | 425.0 | nM | 6.37 |
| CHEMBL1476215 | — | EC50 | = | 432.0 | nM | 6.37 |
| CHEMBL1990071 | — | EC50 | = | 425.0 | nM | 6.37 |
| CHEMBL1532068 | — | EC50 | = | 434.0 | nM | 6.36 |
| CHEMBL2000517 | — | EC50 | = | 486.0 | nM | 6.31 |
| CHEMBL1328792 | — | EC50 | = | 491.0 | nM | 6.31 |
| CHEMBL586135 | — | EC50 | = | 497.0 | nM | 6.30 |
| CHEMBL1304363 | — | EC50 | = | 506.0 | nM | 6.30 |
| CHEMBL3197177 | — | EC50 | = | 536.0 | nM | 6.27 |
| CHEMBL22062 | — | EC50 | = | 536.0 | nM | 6.27 |
| CHEMBL607140 | — | EC50 | = | 543.0 | nM | 6.26 |
| CHEMBL590665 | — | EC50 | = | 570.0 | nM | 6.24 |
| CHEMBL1544633 | — | EC50 | = | 576.0 | nM | 6.24 |
| CHEMBL547285 | — | EC50 | = | 588.0 | nM | 6.23 |
| CHEMBL1373096 | — | EC50 | = | 589.0 | nM | 6.23 |
| CHEMBL1514530 | — | EC50 | = | 617.0 | nM | 6.21 |
| CHEMBL2094567 | — | EC50 | = | 656.0 | nM | 6.18 |
| CHEMBL1570765 | — | EC50 | = | 680.0 | nM | 6.17 |
| CHEMBL1448282 | — | EC50 | = | 687.0 | nM | 6.16 |
| CHEMBL1548492 | — | EC50 | = | 729.0 | nM | 6.14 |
| CHEMBL1983418 | — | EC50 | = | 750.0 | nM | 6.12 |
| CHEMBL1490222 | — | EC50 | = | 763.0 | nM | 6.12 |
| CHEMBL1541973 | — | EC50 | = | 798.0 | nM | 6.10 |
| CHEMBL1424665 | — | EC50 | = | 809.0 | nM | 6.09 |
| CHEMBL578512 | — | EC50 | = | 850.0 | nM | 6.07 |
| CHEMBL600862 | — | EC50 | = | 884.0 | nM | 6.05 |
| CHEMBL1438636 | — | EC50 | = | 976.0 | nM | 6.01 |
| CHEMBL1332404 | — | EC50 | = | 1009.0 | nM | 6.00 |
| CHEMBL1598785 | — | EC50 | = | 1011.0 | nM | 6.00 |
| CHEMBL599924 | — | EC50 | = | 1023.0 | nM | 5.99 |
| CHEMBL585827 | — | EC50 | = | 1032.0 | nM | 5.99 |
| CHEMBL1337500 | — | EC50 | = | 1036.0 | nM | 5.99 |
| CHEMBL3192432 | — | EC50 | = | 1043.0 | nM | 5.98 |
| CHEMBL1337726 | — | EC50 | = | 1047.0 | nM | 5.98 |
| CHEMBL1572967 | — | EC50 | = | 1040.0 | nM | 5.98 |
| CHEMBL1594475 | — | EC50 | = | 1074.0 | nM | 5.97 |
| CHEMBL1543839 | — | EC50 | = | 1069.0 | nM | 5.97 |
| CHEMBL1452116 | — | EC50 | = | 1059.0 | nM | 5.97 |
| CHEMBL1372492 | — | EC50 | = | 1093.0 | nM | 5.96 |
| CHEMBL1405150 | — | EC50 | = | 1126.0 | nM | 5.95 |
| CHEMBL1351755 | — | EC50 | = | 1230.0 | nM | 5.91 |
| CHEMBL1387605 | — | EC50 | = | 1273.0 | nM | 5.89 |
| CHEMBL2095095 | — | EC50 | = | 1293.0 | nM | 5.89 |
| CHEMBL1452421 | — | EC50 | = | 1274.0 | nM | 5.89 |