Assay Detail
Functional
CHEMBL1633575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against thymidine kinase positive Cowpox virus harboring deltacrmA lacZ infected in HFF after 48 hrs by beta-galactosidase assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cowpox virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.86 | 7.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1631219 | — | — | 1 | 7.20 |
| CHEMBL1257073 | TECOVIRIMAT | 4.0 | 1 | 5.75 |
| CHEMBL788 | IDOXURIDINE | 4.0 | 1 | 5.66 |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1631219 | — | EC50 | = | 63.0 | nM | 7.20 |
| CHEMBL1257073 | TECOVIRIMAT | EC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL788 | IDOXURIDINE | EC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL5314375 | CIDOFOVIR | EC50 | = | 15000.0 | nM | 4.82 |