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Target Snapshot

CHEMBL612672 Target Snapshot

Cowpox virus · ORGANISM · Cowpox virus

184Compounds
158Assays
12Approved Drugs
250.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cowpox virus as ChEMBL target CHEMBL612672. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cowpox virus
ORGANISM · Cowpox virus
As of 2026-09-13
ChEMBL target ID
CHEMBL612672
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cowpox virus still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCowpox virus
UniProt AccessionN/A

Cowpox virus

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cowpox virus.

Review nameCowpox virus
OrganismCowpox virus
Clinical Profile

Clinical Phase Distribution

12
Approved
1
Phase II
2
Phase I
Assay Mix

Activity Type Distribution

IC5066.0
EC50184.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL203496 8.15 EC50 7.0 Preclinical
CHEMBL204711 7.7 EC50 20.0 Preclinical
CHEMBL382196 7.7 EC50 20.0 Preclinical
CHEMBL375768 7.7 EC50 20.0 Preclinical
CHEMBL472584 7.7 EC50 20.0 Preclinical
CHEMBL445596 7.7 EC50 20.0 Preclinical
CHEMBL487297 7.7 EC50 20.0 Preclinical
CHEMBL5269665 7.69 IC50 20.3 Preclinical
CHEMBL374302 7.52 EC50 30.0 Preclinical
CHEMBL1162465 7.52 EC50 30.0 Preclinical
Distribution

pChEMBL Value Distribution

43
5.0
32
5.5
17
6.0
7
6.5
10
7.0
9
7.5
1
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

BRINCIDOFOVIR
CHEMBL203321
Approved 2021
TECOVIRIMAT
CHEMBL1257073
Approved 2018
MITOXANTRONE
CHEMBL58
Approved 1987
IDOXURIDINE
CHEMBL788
Approved 1963
Assay Landscape

Assay Landscape

158
Total Assays
117
Tested Compounds
2
Assay Types
Functional — 157 assays, 117 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 157 117 5.5
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine