Assay Detail
Binding
CHEMBL1634342
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]CGP39653 from NMDA receptor in rat brain membrane
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Glutamate NMDA receptor (CHEMBL1907608) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Rattus norvegicus |
Publication
Biostructural and pharmacological studies of bicyclic analogues of the 3-isoxazolol glutamate receptor agonist ibotenic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.02 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL30285 | IBOTENIC ACID | — | 1 | 5.28 |
| CHEMBL72366 | — | — | 1 | 4.75 |
| CHEMBL2092841 | — | — | 1 | - |
| CHEMBL154535 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL30285 | IBOTENIC ACID | Ki | = | 5300.0 | nM | 5.28 |
| CHEMBL72366 | — | Ki | = | 18000.0 | nM | 4.75 |
| CHEMBL2092841 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL154535 | — | Ki | > | 100000.0 | nM | - |