Assay Detail
Functional
CHEMBL1636372
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Antiviral activity against Human herpesvirus 6A GS infected in human HSB-2 cells assessed as inhibition of virus DNA replication after 12 days by quantitative real time PCR
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human herpesvirus 6 (strain GS) |
| Cell Type | HSB-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.29 | 5.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127498 | — | — | 1 | 5.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127498 | — | EC50 | = | 5100.0 | nM | 5.29 |