Assay Detail
Functional
CHEMBL1636377
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Antiviral activity against Murine cytomegalovirus Smith infected in mouse NIH-3T3 cells assessed as inhibition of virus DNA replication after 12 days by plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Murine cytomegalovirus (strain Smith) |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A 6-aminoquinolone compound, WC5, with potent and selective anti-human cytomegalovirus activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.97 | 4.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127498 | — | — | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127498 | — | EC50 | = | 10800.0 | nM | 4.97 |