Assay Detail
ADMET
CHEMBL1638820
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Cytotoxicity against RAMEC assessed as cell viability after 24 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Does conjugation of antioxidants improve their antioxidative/anti-inflammatory potential?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.21 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1631960 | — | — | 1 | 5.58 |
| CHEMBL1631966 | — | — | 1 | 5.55 |
| CHEMBL1631959 | — | — | 1 | 5.54 |
| CHEMBL79129 | KUKOAMINE A | — | 1 | 5.46 |
| CHEMBL1631961 | — | — | 1 | 5.33 |
| CHEMBL1631957 | — | — | 1 | 4.95 |
| CHEMBL1631972 | — | — | 1 | 4.89 |
| CHEMBL1131 | ACITRETIN | 4.0 | 1 | 4.84 |
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 4.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1631960 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL1631966 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL1631959 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL79129 | KUKOAMINE A | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL1631961 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL1631957 | — | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL1631972 | — | IC50 | = | 12900.0 | nM | 4.89 |
| CHEMBL1131 | ACITRETIN | IC50 | = | 14600.0 | nM | 4.84 |
| CHEMBL38 | TRETINOIN | IC50 | = | 18300.0 | nM | 4.74 |