Assay Detail
Functional
CHEMBL1640596
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonistic activity at human 5HT4 receptor expressed in HEK293 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.91 | 10.13 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33884 | — | — | 1 | 10.13 |
| CHEMBL1632154 | — | — | 1 | 9.09 |
| CHEMBL1632155 | — | — | 1 | 6.97 |
| CHEMBL1632156 | — | — | 1 | 5.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33884 | — | Ki | = | 0.07413 | nM | 10.13 |
| CHEMBL1632154 | — | Ki | = | 0.8128 | nM | 9.09 |
| CHEMBL1632155 | — | Ki | = | 107.15 | nM | 6.97 |
| CHEMBL1632156 | — | Ki | = | 3630.78 | nM | 5.44 |