Assay Detail
Binding
CHEMBL1640797
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MMP9 in cell-free system by fluorescent spectroscopy
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure based optimization of chromen-based TNF-α converting enzyme (TACE) inhibitors on S1' pocket and their quantitative structure-activity relationship (QSAR) study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.64 | 4.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1630091 | — | — | 1 | 4.64 |
| CHEMBL1630098 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1630091 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL1630098 | — | IC50 | = | 460000.0 | nM | - |