Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1640982

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A253 cells after 96 hrs by sulforhodamine B assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A253
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and biological activity of some antitumor active derivatives from glycyrrhetinic acid.
Csuk R, Schwarz S, Kluge R, Ströhl D.
Eur J Med Chem (2010) 45 : 5718 -5723
PubMed 20884085 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 12 5.26 5.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1630879 1 5.95
CHEMBL1629726 1 5.76
CHEMBL1630878 1 5.64
CHEMBL1630877 1 5.59
CHEMBL1630880 1 5.52
CHEMBL1630876 1 5.44
CHEMBL1630881 1 5.33
CHEMBL1630882 1 5.26
CHEMBL1630875 1 5.21
CHEMBL1271483 1 4.71
CHEMBL1630874 1 4.59
CHEMBL230006 ENOXOLONE 2.0 1 4.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1630879 IC50 = 1120.0 nM 5.95
CHEMBL1629726 IC50 = 1740.0 nM 5.76
CHEMBL1630878 IC50 = 2270.0 nM 5.64
CHEMBL1630877 IC50 = 2560.0 nM 5.59
CHEMBL1630880 IC50 = 3010.0 nM 5.52
CHEMBL1630876 IC50 = 3640.0 nM 5.44
CHEMBL1630881 IC50 = 4650.0 nM 5.33
CHEMBL1630882 IC50 = 5480.0 nM 5.26
CHEMBL1630875 IC50 = 6190.0 nM 5.21
CHEMBL1271483 IC50 = 19420.0 nM 4.71
CHEMBL1630874 IC50 = 25540.0 nM 4.59
CHEMBL230006 ENOXOLONE IC50 = 80780.0 nM 4.09