Assay Detail
Functional
CHEMBL1645779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Human immunodeficiency virus 1 NL4-3 infected in MT4 lymphocytes assessed as p24 antigen level by ELISA
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 5.95 | 7.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404519 | BEVIRIMAT | 2.0 | 1 | 7.09 |
| CHEMBL1644817 | EPICEANOTHIC ACID | — | 1 | 4.81 |
| CHEMBL23236 | BETULIN | — | 1 | - |
| CHEMBL1644922 | — | — | 1 | - |
| CHEMBL1644923 | — | — | 1 | - |
| CHEMBL1644924 | — | — | 1 | - |
| CHEMBL1644925 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404519 | BEVIRIMAT | EC50 | = | 82.0 | nM | 7.09 |
| CHEMBL1644817 | EPICEANOTHIC ACID | EC50 | = | 15600.0 | nM | 4.81 |
| CHEMBL23236 | BETULIN | EC50 | - | — | - | |
| CHEMBL1644922 | — | EC50 | - | — | - | |
| CHEMBL1644923 | — | EC50 | - | — | - | |
| CHEMBL1644924 | — | EC50 | - | — | - | |
| CHEMBL1644925 | — | EC50 | - | — | - |