Assay Detail
Binding
CHEMBL1646505
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of T-type alpha1G calcium channel
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Voltage-dependent T-type calcium channel subunit alpha-1G (CHEMBL4641) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1423 | PIMOZIDE | 4.0 | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1423 | PIMOZIDE | Kd | = | 40.0 | nM | 7.40 |