Assay Detail
Functional
CHEMBL1647708
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 12 hrs by Broth microdilution method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Highly brominated antimicrobial metabolites from a marine Pseudoalteromonas sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.02 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1235156 | PENTABROMOPSEUDILIN | — | 1 | 7.00 |
| CHEMBL262777 | VANCOMYCIN | 4.0 | 1 | 6.04 |
| CHEMBL1641934 | — | — | 1 | 5.71 |
| CHEMBL32991 | BROMOPHENE | — | 1 | 5.67 |
| CHEMBL1641935 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1235156 | PENTABROMOPSEUDILIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL262777 | VANCOMYCIN | IC50 | = | 910.0 | nM | 6.04 |
| CHEMBL1641934 | — | IC50 | = | 1930.0 | nM | 5.71 |
| CHEMBL32991 | BROMOPHENE | IC50 | = | 2140.0 | nM | 5.67 |
| CHEMBL1641935 | — | IC50 | = | 2190.0 | nM | 5.66 |