Assay Detail
Binding
CHEMBL1648958
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to androgen receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Tetrahydroquinoline glucocorticoid receptor agonists: discovery of a 3-hydroxyl for improving receptor selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.43 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL258191 | — | — | 1 | 7.24 |
| CHEMBL1644765 | — | — | 1 | 6.40 |
| CHEMBL1644759 | — | — | 1 | 6.05 |
| CHEMBL1644761 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL258191 | — | Ki | = | 57.0 | nM | 7.24 |
| CHEMBL1644765 | — | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL1644759 | — | Ki | = | 900.0 | nM | 6.05 |
| CHEMBL1644761 | — | Ki | = | 915.0 | nM | 6.04 |