Assay Detail
Functional
CHEMBL1653233
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Antiviral activity against EV71 harboring VP1 protease V192M mutant gene infected in human RD cells assessed as inhibition of viral plaque formation 16 hrs by plaque formation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus A71 |
| Cell Type | RD |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.62 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL83661 | — | — | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL83661 | — | EC50 | = | 240.0 | nM | 6.62 |