Assay Detail
Binding
CHEMBL1656374
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Inhibition of cKIT by TR-FRET based LanthaScreen assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Mast/stem cell growth factor receptor Kit (CHEMBL1936) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Kinase inhibition by deoxy analogues of the resorcylic lactone L-783277.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.94 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2012519 | — | — | 1 | 6.52 |
| CHEMBL1651521 | — | — | 1 | 6.17 |
| CHEMBL1651522 | — | — | 1 | 5.12 |
| CHEMBL1651523 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2012519 | — | IC50 | = | 303.0 | nM | 6.52 |
| CHEMBL1651521 | — | IC50 | = | 673.0 | nM | 6.17 |
| CHEMBL1651522 | — | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL1651523 | — | IC50 | > | 10000.0 | nM | - |