Assay Detail
Functional
CHEMBL1658352
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Poliovirus 10238 serotype PV1 obtained from circulating vaccine infected in pig LLC-MK2 cells assessed as inhibition of viral-replication induced cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human enterovirus C |
| Cell Type | LLC-MK2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro antiviral activity of V-073 against polioviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.85 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1235858 | — | — | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1235858 | — | EC50 | = | 14.0 | nM | 7.85 |