Assay Detail
Functional
CHEMBL1658844
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Antiviral activity against Human herpesvirus 8 infected in human BCBL1 cells assessed as decrease in viral DNA accumulation after 7 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human gammaherpesvirus 8 |
| Cell Type | BCBL1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.19 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 7.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5314375 | CIDOFOVIR | EC50 | = | 64.0 | nM | 7.19 |