Assay Detail
Functional
CHEMBL1663957
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Antiproliferative activity against human LNCAP cells after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LNCaP |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1649601 | — | — | 1 | 4.96 |
| CHEMBL1036 | HYDROXYHALOPERIDOL | — | 1 | - |
| CHEMBL1469 | PHENYLBUTANOIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1649601 | — | IC50 | = | 10870.0 | nM | 4.96 |
| CHEMBL1036 | HYDROXYHALOPERIDOL | IC50 | = | 177000.0 | nM | - |
| CHEMBL1469 | PHENYLBUTANOIC ACID | IC50 | = | 2324000.0 | nM | - |