Assay Detail
Binding
CHEMBL1664440
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Inhibition of mushroom tyrosinase after 10 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identifying chelators for metalloprotein inhibitors using a fragment-based approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.91 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121188 | TROPOLONE | — | 1 | 6.40 |
| CHEMBL1650615 | — | — | 1 | 5.42 |
| CHEMBL424 | SALICYLIC ACID | 3.0 | 1 | 4.00 |
| CHEMBL1650602 | — | — | 1 | 3.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121188 | TROPOLONE | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL1650615 | — | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL424 | SALICYLIC ACID | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL1650602 | — | IC50 | = | 159000.0 | nM | 3.80 |