Assay Detail
Binding
CHEMBL1664679
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Inhibition of PTP1B
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.34 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1650889 | — | — | 1 | 6.72 |
| CHEMBL1650891 | — | — | 1 | 6.69 |
| CHEMBL1650892 | — | — | 1 | 6.67 |
| CHEMBL1650893 | — | — | 1 | 6.66 |
| CHEMBL1650918 | — | — | 1 | 4.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1650889 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL1650891 | — | IC50 | = | 205.0 | nM | 6.69 |
| CHEMBL1650892 | — | IC50 | = | 214.0 | nM | 6.67 |
| CHEMBL1650893 | — | IC50 | = | 217.0 | nM | 6.66 |
| CHEMBL1650918 | — | IC50 | = | 11500.0 | nM | 4.94 |