Assay Detail
Binding
CHEMBL1664682
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HePTP
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 7 (CHEMBL2219) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.19 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1650889 | — | — | 1 | 5.43 |
| CHEMBL1650891 | — | — | 1 | 5.43 |
| CHEMBL1650892 | — | — | 1 | 5.39 |
| CHEMBL1650893 | — | — | 1 | 5.20 |
| CHEMBL1650918 | — | — | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1650889 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL1650891 | — | IC50 | = | 3690.0 | nM | 5.43 |
| CHEMBL1650892 | — | IC50 | = | 4070.0 | nM | 5.39 |
| CHEMBL1650893 | — | IC50 | = | 6360.0 | nM | 5.20 |
| CHEMBL1650918 | — | IC50 | = | 32000.0 | nM | 4.50 |