Assay Detail
Binding
CHEMBL1664683
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Inhibition of LAR
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Receptor-type tyrosine-protein phosphatase F (CHEMBL3521) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.48 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1650891 | — | — | 1 | 4.62 |
| CHEMBL1650889 | — | — | 1 | 4.59 |
| CHEMBL1650892 | — | — | 1 | 4.44 |
| CHEMBL1650893 | — | — | 1 | 4.40 |
| CHEMBL1650918 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1650891 | — | IC50 | = | 23700.0 | nM | 4.62 |
| CHEMBL1650889 | — | IC50 | = | 25500.0 | nM | 4.59 |
| CHEMBL1650892 | — | IC50 | = | 36100.0 | nM | 4.44 |
| CHEMBL1650893 | — | IC50 | = | 39900.0 | nM | 4.40 |
| CHEMBL1650918 | — | IC50 | = | 44400.0 | nM | 4.35 |