Assay Detail
Functional
CHEMBL1667321
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Antifungal activity against Aspergillus fumigatus B5233 conidia after 16 hrs by fluorescence-based microplate assay at pH 7.2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Aspergillus fumigatus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.64 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL70927 | DEFERIPRONE | 4.0 | 1 | 5.89 |
| CHEMBL1413 | CICLOPIROX | 4.0 | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL70927 | DEFERIPRONE | IC50 | = | 1290.0 | nM | 5.89 |
| CHEMBL1413 | CICLOPIROX | IC50 | = | 4220.0 | nM | 5.38 |